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AQA GCSE Biology (8461) — revision checklist

AQA · GCSE 8461
97 spec points

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Verified against AQA 8461 (2026 spec)

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4.1Cell biology

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  • Eukaryotes and prokaryotes

    4.1.1.1

  • Animal and plant cells

    4.1.1.2

  • Cell specialisation

    4.1.1.3

  • Cell differentiation

    4.1.1.4

  • Microscopy

    4.1.1.5

  • Culturing microorganisms (biology only)

    4.1.1.6

  • Chromosomes

    4.1.2.1

  • Mitosis and the cell cycle

    4.1.2.2

  • Stem cells

    4.1.2.3

  • Diffusion

    4.1.3.1

  • Osmosis

    4.1.3.2

  • Active transport

    4.1.3.3

4.2Organisation

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  • Principles of organisation

    4.2.1

  • The human digestive system

    4.2.2.1

  • The heart and blood vessels

    4.2.2.2

  • Blood

    4.2.2.3

  • Coronary heart disease: a non-communicable disease

    4.2.2.4

  • Health issues

    4.2.2.5

  • The effect of lifestyle on some non-communicable diseases

    4.2.2.6

  • Cancer

    4.2.2.7

  • Plant tissues

    4.2.3.1

  • Plant organ system

    4.2.3.2

4.3Infection and response

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  • Communicable (infectious) diseases

    4.3.1.1

  • Viral diseases

    4.3.1.2

  • Bacterial diseases

    4.3.1.3

  • Fungal diseases

    4.3.1.4

  • Protist diseases

    4.3.1.5

  • Human defence systems

    4.3.1.6

  • Vaccination

    4.3.1.7

  • Antibiotics and painkillers

    4.3.1.8

  • Discovery and development of drugs

    4.3.1.9

  • Producing monoclonal antibodies

    4.3.2.1

  • Uses of monoclonal antibodies

    4.3.2.2

  • Detection and identification of plant diseases

    4.3.3.1

  • Plant defence responses

    4.3.3.2

4.4Bioenergetics

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  • Photosynthetic reaction

    4.4.1.1

  • Rate of photosynthesis

    4.4.1.2

  • Uses of glucose from photosynthesis

    4.4.1.3

  • Aerobic and anaerobic respiration

    4.4.2.1

  • Response to exercise

    4.4.2.2

  • Metabolism

    4.4.2.3

4.5Homeostasis and response

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  • Homeostasis

    4.5.1

  • Structure and function

    4.5.2.1

  • The brain (biology only)

    4.5.2.2

  • The eye (biology only)

    4.5.2.3

  • Control of body temperature (biology only)

    4.5.2.4

  • Human endocrine system

    4.5.3.1

  • Control of blood glucose concentration

    4.5.3.2

  • Maintaining water and nitrogen balance in the body (biology only)

    4.5.3.3

  • Hormones in human reproduction

    4.5.3.4

  • Contraception

    4.5.3.5

  • The use of hormones to treat infertility (HT only)

    4.5.3.6

  • Negative feedback (HT only)

    4.5.3.7

  • Control and coordination

    4.5.4.1

  • Use of plant hormones (HT only)

    4.5.4.2

4.6Inheritance, variation and evolution

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  • Sexual and asexual reproduction

    4.6.1.1

  • Meiosis

    4.6.1.2

  • Advantages and disadvantages of sexual and asexual reproduction (biology only)

    4.6.1.3

  • DNA and the genome

    4.6.1.4

  • DNA structure (biology only)

    4.6.1.5

  • Genetic inheritance

    4.6.1.6

  • Inherited disorders

    4.6.1.7

  • Sex determination

    4.6.1.8

  • Variation

    4.6.2.1

  • Evolution

    4.6.2.2

  • Selective breeding

    4.6.2.3

  • Genetic engineering

    4.6.2.4

  • Cloning (biology only)

    4.6.2.5

  • Theory of evolution (biology only)

    4.6.3.1

  • Speciation (biology only)

    4.6.3.2

  • The understanding of genetics (biology only)

    4.6.3.3

  • Evidence for evolution

    4.6.3.4

  • Fossils

    4.6.3.5

  • Extinction

    4.6.3.6

  • Resistant bacteria

    4.6.3.7

  • Classification of living organisms

    4.6.4

4.7Ecology

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  • Communities

    4.7.1.1

  • Abiotic factors

    4.7.1.2

  • Biotic factors

    4.7.1.3

  • Adaptations

    4.7.1.4

  • Levels of organisation

    4.7.2.1

  • How materials are cycled

    4.7.2.2

  • Decomposition (biology only)

    4.7.2.3

  • Impact of environmental change (biology only) (HT only)

    4.7.2.4

  • Biodiversity

    4.7.3.1

  • Waste management

    4.7.3.2

  • Land use

    4.7.3.3

  • Deforestation

    4.7.3.4

  • Global warming

    4.7.3.5

  • Maintaining biodiversity

    4.7.3.6

  • Trophic levels

    4.7.4.1

  • Pyramids of biomass

    4.7.4.2

  • Transfer of biomass

    4.7.4.3

  • Factors affecting food security

    4.7.5.1

  • Farming techniques

    4.7.5.2

  • Sustainable fisheries

    4.7.5.3

  • Role of biotechnology

    4.7.5.4

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